VCAM1 and breast neoplasm: proved that the α4β1 integrin, necessary for MC adhesion to the vascular cell adhesion molecule 1 (VCAM‐1) on the breast tumor cells was well preserved on the MCM after PLGA NP coating via extrusion.[152b] The enveloped particles had a diameter of ≈177–197 nm, a zeta‐potential of −16.5 mV, good serum stability within 120 h, high drug loading capacity, and sustained drug release over 72 h.