UIQ, upper inner quadrant; UOQ, upper outer quadrant; LOQ, lower outer quadrant; LIQ, lower inner quadrant; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; DCIS, ductal carcinoma in situ; HER2, human epidermal growth factor receptor 2; ER, estrogen receptor; PR, progesterone receptor; LN, lymph node. Here, ESR1 is linked to invasive ductal breast carcinoma.