ZEB1 and hepatocellular carcinoma: In addition, overexpression of ZEB1 in both HUH-7 and Hep3B cells (Figure 1F) that express relatively lower levels of ZEB1 as compared with MHCC-97H and HCC-LM3 cells (Figure 2L), dramatically promoted glucose uptake (Figure 1G) and lactate production (Figure 1H).