We found that MYBL2 mRNA levels were robustly upregulated in metastatic PCa samples compared with those in non-metastatic PCa or benign tissues, in T3-4 tumors compared with T2, in N1 PCa compared with N0, and correlated significantly with the Gleason score and PSA level (Figure 1A and Figure S1A-E). Here, MYBL2 is linked to posterior cortical atrophy.