Notably, MYBL2 overexpression dramatically accelerated the growth of LNCaP and MDA PCa 2b cells, while MYBL2 silencing markedly inhibited the growth rate of LNCaP-AI cells; the pro-proliferation function of MYBL2 on PCa cells was more remarkable in the castrated condition with CSS medium (Figure 2C). This evidence concerns the gene MYBL2 and posterior cortical atrophy.