Matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) play an important role in tumor invasion and migration .HeLa cells were treated with different concentrations of alloimperatorin for 48 hours, and western blot was used to test the expression of alloimperatorin on the HeLa cells .The results (Figures 7(a) and 7(b)) showed that alloimperatorin inhibited the expression of migration protein, which has a clear trend compared with the control group. The gene discussed is MMP2; the disease is neoplasm.