Four of the enriched target genes have been reported to be associated with autoimmune diseases in the GWAS catalogue, i.e. IL-6 (juvenile idiopathic arthritis), PRDM1 (systemic lupus erythematosus, inflammatory bowel disease), IL-13 (psoriasis, inflammatory bowel disease), and TLR4 (inflammatory bowel disease). This evidence concerns the gene IL13 and juvenile idiopathic arthritis.