These included anti-complement 3 (lupus), anti-complement C1q (lupus), anti-SP100 (lupus), PR-3 (vasculitis), anti-LC-1 (autoimmune hepatitis), anti-Nup62 (primary biliary cirrhosis), anti-MI-2 (myositis), and anti-vimentin (rheumatoid arthritis) (Figure 9C). Here, VIM is linked to primary biliary cholangitis.