TNF and rheumatoid arthritis: The lowest basal/control TNF-α levels in the whole blood supernatants were measured in the plasma samples of patients with RA with the remission form of the disease [basal level with a median of 5 pg/ml; SA1-induced concentration at a median level of 30 pg/ml, and SZR72 suppressed it to 15 pg/m as a median (Figure 3)].