MTOR and primitive neuroectodermal tumor: When adjusted for the age of the patient and location of the PNET, the mixed models also demonstrated an association between mTOR use and the size of the PNET with patients on mTOR inhibitors having PNETs that were smaller compared to the size measured in patients not taking mTOR inhibitors (difference of 5.5 mm, 95% CI: 2.1–9.0 mm) (Figure 2).