Beyond the recommended doses, DHA and EPA extended the lifespan in a dose-dependent manner, downregulated the levels of anti-dsDNA antibodies and the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α, and attenuated glomerulonephritis in SLE patients (Halade et al., 2013). Here, TNF is linked to systemic lupus erythematosus.