Because the TASK-1 channel is involved in many pathological processes, a modulation of the channel by drugs could be a promising strategy against AF, sleep apnea or drug-induced ventilatory depression, sleep disorders, neurodegenerative disorders, major depression, and/or malignancy (Chokshi et al., 2015; Kiper et al., 2015; Wiedmann et al., 2016). This evidence concerns the gene KCNK3 and sleep apnea syndrome.