KCNK3 and atrial fibrillation: To satisfy this unmet treatment need the underlying causes of AF have become a focus of research, leading to recognition of the tandem of P domains in a weak inward rectifying K+ channel (TWIK)-related acid sensitive K+ channel 1 (TASK-1), a member of the two-pore-domain potassium (K2P) channel family (Schmidt et al., 2015, 2017; Ravens, 2017).