APOE and Alzheimer disease: Similarly, Modrego et al. (2011) reported that, when the ratio of NAA/Cr in the middle and the rear of bilateral parietal lobes was ≤ 1.43, the accuracy and specificity of predicting the conversion of MCI to possible AD were 0.741 and 0.837, respectively, when included in the APOE genotype and memory tests for analysis, where the accuracy was higher.