As the most important glycan ligand for E-selectin (which is expressed on the surfaces of endothelial cells)10,30–32, sLex is present on the surfaces of many types of cancer cells, including breast IMPC cells7,12–16, and it plays an important role in the extravasation of cancer cells from the blood or lymph vessels, thereby promoting the migration of cancer cells to distant organs. This evidence concerns the gene SELE and cancer.