HLA-DRB1 and anti-glomerular basement membrane disease: A similar effect has already been noted in the case of Goodpasture’s syndrome with higher frequency of Tregs specific for the Collagen IV autoantigen α3135-145 in HLA-DRB1*01:01+ (disease-resistant) individuals, compared to HLA-DRB1*15:01+ (disease-susceptible) individuals, regarding the same autoantigen specificity, albeit with binding register shifted by one residue41.