CRP and macular degeneration: rs557998486 was associated with increased risk of macular degeneration in UK Biobank under the recessive model (OR [CI 95%] = 7.6 [1.5–37.3], p = 4.1 × 10−2), eye surgery (beta [CI 95%] = 1.6 [0.6–2.6], p = 1.17 × 10−3) (Supplementary Data 8), and with increased C-reactive protein, a known biomarker for macular degeneration37,38 (beta [CI 95%] = 1.1 [0.7–1.5], p = 1.15 × 10−4) (Supplementary Data 9).