TNF and neoplasm: Indeed, IPLD-treated mice had substantially higher CRT exposure, lower tumour PD-L1 expression (Fig. 6a-c), and more mDCs (Fig. 6d,e) and active CTLs (Fig. 6f,g) but less Tregs (Fig. 6k,l), as well as higher levels of antitumour-associated cytokines including IFN-γ, TNF-α, IL-2, and IL-6 (Fig. 6n) but unchanged anti-inflammatory cytokine IL-10 (known detrimental to antitumour immune response65).