Firstly, ONCOMINE was used to perform a meta‐analysis to compare the mRNA levels of FN1, CXCL8, CXCL10, SPP1, FOXM1, AURKA, ISG15, PLAUR, TPX2, and BIRC5 between OSCC and non-tumor oral tissues. The gene discussed is CXCL8; the disease is neoplasm.