Exceptions to this are CRBN, DDX17, GPER, DISC1, LRP3, and TLR2. Note that DISC1 and TLR2 are on the DisGenet [45] Late onset Alzheimer disease gene set, but that we found no significant enrichment using DisGenet for any method (our test, Limma, Wilcoxon). This evidence concerns the gene LRP3 and Alzheimer disease.