SDC2 and Ehlers-Danlos syndrome, musculocontractural type: In our study, by exploring the expression patterns of IRGs in ATCs, PTCs and normal thyroid tissues in the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, a two-gene risk score signature comprising MMP9 and SDC2 with predictive power for dedifferentiation and survival was constructed.