For instance, HOTAIR/miR-149-5p/HNRNPA1 axis promotes the cell growth, migration, and invasion in NSCLC [46]; FAM83A-AS1/miR-150-5p/MMP14 regulates LUAD progression and invasion [45]; BANCR/miR-338-3p/IGF1R network regulated Raf/MEK/ERK pathway, thereby encouraging the proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of esophageal cancer [47]. The gene discussed is MMP14; the disease is esophageal cancer.