Particularly important for a good long-term prognosis were albumin infusion for hypoalbuminemia, administration of diuretics for ascites and lower limb edema, ammonia-lowering therapy for the prevention and treatment of hepatic encephalopathy, antibacterial treatment for infectious diseases, and prophylactic treatment for esophageal varices (endoscopic variceal ligation or endoscopic injection sclerotherapy). The gene discussed is ALB; the disease is esophageal varices.