We observed immunohistochemical staining for platelets associated with eosinophils in vessels of EoE biopsies [3] and we earlier demonstrated in in vitro experiments that interaction of P-selectin, which is expressed on the surface of activated platelets, with eosinophils activates eosinophil α4β1 integrin [28]. This evidence concerns the gene SELP and eosinophilic esophagitis.