ZIKV infection in embryonic mouse cortex and human neural progenitors dysregulate a number of known microcephaly-associated genes such as MCPH1 (Microcephalin), CENPF (Centromere Protein F), TBR2 (T-box brain protein 2), RBBP8 (RB binding protein 8), AXL (AXL receptor tyrosine kinase), and ASPM (Assembly factor for spindle microtubules) [31,35]. Here, ASPM is linked to Zika virus infectious disease.