For ETV6-RUNX1 subtype specific locus in IGF2BP1, although only 77 patients carried ETV6-RUNX1 fusion, the risk allele frequency of rs10853104 has no obvious difference between patient and non-ALL controls (12.3% vs. 12.4%), suggesting that insignificance of this locus is probably induced by ethnic specificity rather than the small sample size. Here, IGF2BP1 is linked to acute lymphoblastic leukemia.