COMMD7 and cancer: Therefore, in this study, we aimed to ascertain the relationship between the expression level of COMMD7 and the prognosis of AML by the following three steps: First of all, RNA sequencing (RNA-seq) data of AML samples from the cancer genome atlas (TCGA) and Genotype-Tissue Expression (GTEx) were acquired to analyze the expression of the core gene COMMD7. Subsequently, functional enrichment analysis of COMMD7 was via GO, KEGG, GSEA, immune cell infiltration analysis, and protein-protein interaction (PPI) network.