FGFR1 and central nervous system cancer: The great majority of these pathways have been directly or indirectly related to MB in the literature, such as the interplay between the embryonic morphogens Nodal and Hedgehog in brain development (Rohr et al., 2001), the activation of Activin signaling in a subset of G3 subgroup (Morabito et al., 2019), the role of FGFR1 in gliomas (Egbivwie et al., 2019), and the importance of carbohydrate antigen recognition in MB (Read et al., 2009).