Comparison of haplotypes between the two groups revealed that haplotype T-A-G-T in ApoB gene was overrepresented in cases (18.10%) compared with controls (12.76%) (Simulated P = 0.045), and haplotype T-A-G-T was associated with a 33% increased risk of DKD (OR = 1.33, 95% CI: 1.04, 1.70). This evidence concerns the gene APOB and diabetic kidney disease.