CD79A and peripheral arterial disease: The importance of IgA comes from studies on patients with Primary Antibody Deficiencies (PAD), where the impaired IgA production, and IgA antibody-mediated responses, are associated to the susceptibility to respiratory and gastrointestinal infections and their recurrence (Hammarström et al., 2000; Tangye et al., 2020), to upper respiratory tract colonization (Pulvirenti et al., 2020a), and to the risk to develop chronic respiratory diseases (Quinti et al., 2011).