N-acetylglucosaminyltransferase-V (GnT-V) and ST6 N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 1 (ST6GALNAC1) facilitated glycosylation have been reported to control stemness of colon cancer cells through WNT signaling and Akt pathway respectively (41, 42, 44). This evidence concerns the gene ST6GALNAC1 and malignant colon neoplasm.