CPAP and neoplasm: To test if the EMT-like features and enhanced invasiveness of CPAP-depleted OSCC cells can translate into rapid tumor growth in vivo, SCC-Cal27 and UM-SCC-74B cells stably expressing control-shRNA and CPAP-shRNA under a doxycycline inducible promoter (Figure 2A) were injected s.c. into the flanks of athymic-nude mice.