Stable CPAP depletion was performed in 3 oral cancer cell-lines with: 1) an epithelial phenotype (SCC-Cal27), 2) a mesenchymal phenotype of primary tumor origin (UM-SCC-74A), and 3) a mesenchymal phenotype of recurrent tumor origin (UM-SCC-74B). Here, CPAP is linked to lip and oral cavity carcinoma.