Therefore, this study aimed to depict the prevalence of receptor status and molecular subtypes in women with breast cancer treated at Potchefstroom Regional Hospital, South Africa and to analyze the association of molecular subtypes with other prognostic factors such as the age of the patients, menopause status with age as a proxy, stage of the disease, lymph nodes status, histological type, tumor grade, tumor size and Ki-67 proliferation index. The gene discussed is MKI67; the disease is breast cancer.