SLC20A2 and Cognitive impairment: However, Slc20a2-HO mice only exhibited long-term spatial learning memory impairments and sensorimotor gating deficits, as revealed by MWM and PPI tests, which corresponded with cognitive impairments and psychiatric signs observed in patients with SLC20A2 mutation (Nicolas et al., 2013a, 2015; Donzuso et al., 2019; Guo et al., 2019).