The homeostatic balance governed by a tight control of both AMP transcripts and Duox expression is further confirmed by the effect of the mechanism exerted by the pathogenic fungus Beauveria bassiana: this fungus induces dysbiosis in the mosquito midgut by altering the expression of AMP transcripts and Duox with the secretion of the toxin oosporein, inducing bacterial growth, promoting the overgrowth of the opportunistic bacteria S. marcescens, which, once in the hemocoel, favors septicemia and thus the killing of mosquitoes (Wei et al., 2017). This evidence concerns the gene DUOX1 and Sepsis.