Particularly, eleven single nucleotide polymorphisms (SNPs) have been examined and authors have proved that three of them (PNPLA3 rs738409, TM6SF2 rs58542926, and GCKR rs1260326) are strongly associated to hepatic steatosis in children; while the variant ELOVL2 rs2236212 have a modest connection with NAFLD development, independently of age, sex, and z-BMI (101). Here, PNPLA3 is linked to metabolic dysfunction-associated steatotic liver disease.