Compared with the MCAO group, MCAO + ROSI treatment significantly attenuated the decrease in the protein level of GPx4 in mice caused by stroke (0.27 ± 0.06 vs 0.36 ± 0.04, p ≤ 0.05; n = 5, one-way ANOVA, Figures 5A,C). The gene discussed is GPX4; the disease is stroke disorder.