Compared with the MCAO group, MCAO + ROSI treatment significantly suppressed the increase in the protein level of ACSL4 in mice caused by stroke (MCAO group vs MCAO + ROSI group: 0.41 ± 0.05 vs 0.32 ± 0.05, p ≤ 0.05; n = 5, one-way ANOVA, Figures 5A,B). The gene discussed is ACSL4; the disease is Stroke.