SOD1 and stroke disorder: Compared with the MCAO group, MCAO + ROSI treatment significantly attenuated the decrease of SOD level and the increased MDA level in mice caused by stroke (SOD: 56.06 ± 13.16 vs 78.07 ± 14.09, MDA: 19.19 ± 3.08 vs 13.69 ± 2.35, p ≤ 0.05; n = 5, one-way ANOVA, Figures 6E,F).