Our results show that both invasion (Fig. 1F) and migration (Fig. 1G) were attenuated in the miR-335 mimic-transfected 786-O cells, and the qPCR (Fig. 1H)and western blot results (Fig. 1I) of E-cadherin and Vimentin also show that miR-335 inhibits tumor metastatic capacity. The gene discussed is CDH1; the disease is neoplasm.