CCR6 and uterine cervix carcinoma in situ: However, when CD45RA+/CCR6+ ‘immunoscore’ was used, we observed an increasing number of CC women presenting a high ‘immunoscore’ compared to CIN I (p < 0.01.043, χ2 = 10.9), CIN II (p < 0.05, χ2 = 7.0) and CIN III (p < 0.01, χ2 = 9.92, Fig. 6E).