In evaluating the 44 proteins that overlapped in between the native kidney CKD and post-kidney transplant CKD groups, the following were found to correlate significantly with uACR: desmocollin-2 (DSC-2), cystatin C, fatty acid-binding protein, liver-type (FABPL), regenerating islet-derived protein 4 (REG-4), IGFBP-6, CD59, ephrin-A2, A4, and A5, and EFN-B2. This evidence concerns the gene DSC2 and chronic kidney disease.