More specifically, the most robust BMAL1 peak (see the maximum track height on the Y-axis) that was found in both non-obese and obese OAPs corresponded to a gene coding for the activating chromatin modifier Histone-lysine N-methyltransferase 2A, MLL1 (KMT2A); yet, BMAL1 peak value at this locus was lower in obesity (Fig. 6D, by ~−14%, P < 0.05). This evidence concerns the gene KMT2A and obesity due to melanocortin 4 receptor deficiency.