Addressing these questions is particularly important in the light of the essential role that BAP1 plays as a tumor suppressor (Ventii et al. 2008; Dey et al. 2012; Carbone et al. 2013; Murali et al. 2013; Daou et al. 2015) and could provide important new insight into how BAP1 dysfunction causes cellular transformation. Here, BAP1 is linked to neoplasm.