INS and Hypoglycemia: The percentage of patients on intravenous insulin infusion at 48 hours from admission increased from 6% to 35%.<h4>Conclusion</h4>The phased implementation of a formal education program, fostering the use of electronic insulin therapy protocols and dynamic manuals, received good adherence and has shown to be safe and effective for blood glucose control in critically ill patients, with a concomitant decrease in hypoglycemia.