TBC1D24 mutations have been reported in patients with DOORS (deafness onychodystrophy, osteodystrophy, mental retardation and seizures [13]) syndrome, progressive myoclonic epilepsy [14], early infantile EE [15] and malignant migrating partial seizures of infancy (MMPSI, [16]). The gene discussed is TBC1D24; the disease is malignant migrating partial seizures of infancy.