Recently, on the basis of the assumption that the structure of full-length ACE2 may be disclosed in the presence of B0AT1, Yan et al. reported the 3D structure of the hACE2-B0AT1 complex and the RBD-ACE2-B0AT1 ternary complex that provides the structural basis for understanding SARS-CoV-2 recognition and infection by hACE2 [31]. Here, ACE2 is linked to infection.