When all MAIT cells were analyzed together, IFN-γ-production was lower in MAIT cells from the tumors than in cells from the unaffected colon (median 33% in tumor-derived and 50% in unaffected colon MAIT cells, p < 0.05), while there were no significant differences in total MAIT cell production of GrB (median 46% vs 28%), IL-2 (median 26% vs 21%), or TNF (median 61% vs 41%) between cells from tumors and unaffected tissue. The gene discussed is IFNG; the disease is neoplasm.