On day 11 after inoculation, when the tumor volume reached approximately 40 mm3, we divided mice into 4 groups and treated them with 200 μg control IgG, αmPD-1 that suppresses tumor growth by blocking the binding between mouse PD-1 and human PD-L1 (Supplemental Figure 7, B–D), H1A, or 1:1 mixed αmPD-1 and H1A, respectively. This evidence concerns the gene CD274 and neoplasm.