ITGAM and congestive heart failure: Using Flow cytometry, our data demonstrated that the percentage of macrophages (defined as CD45+/CD11b+ cells) in SGs was markedly higher in CHF rats than that in sham rats (4.60 ± 0.47% in CHF rats vs. 2.07 ± 0.13% in sham rats, p < 0.05, Fig. 2C).