Such DAMPs include adenine nucleotide triphosphate (ATP), which serves as chemoattractant for antigen presenting cells, annexin A1 (ANXA1), which acts as a homing signal for dendritic cells, calreticulin, which functions as an phagocytosis-inducing signal and high mobility group box 1 (HMGB1), which stimulates the maturation of dendritic cells (DCs) and the presentation of tumor antigens to T cells. The gene discussed is HMGB1; the disease is neoplasm.