A number of 61 deleterious variants in the ACE2 gene including R219C, R219H, M383T, P389H, D427Y, R514G, R708W, R710H, R710C, R716C, L731F, and R768W, have been reported to influence susceptibility to COVID-19 (Hou et al. 2020). The gene discussed is ACE2; the disease is COVID-19.