In addition, studies have found that CIRC_0067934 directly inhibits the interaction between mRNA 3′-UTR of FZD5 and miR-1324 and activates the FZD5/Wnt/β-catenin signal pathway to promote the proliferation, invasion, and migration of hepatocellular carcinoma cells [29]. This evidence concerns the gene FZD5 and hepatocellular carcinoma.