Thus, PCaA-SEV vaccination led toenhanced infiltration of anti-tumor CD8+ T cells in the tumor microenvironment.Taken together, our findings suggested that EP mediated enhanced delivery of these DNAvaccines were able to generate PCaA specific CD8+T cells and elevate theirlevels in the tumor microenvironment leading to improved survival of the mice bearingprostate tumor. Here, CD8A is linked to neoplasm.